SIBUTRAMINE HCL
sibutramine hydrochloride
CAS: 84485-00-7
Molecular Formula: C17H27Cl2N
SIBUTRAMINE HCL - Names and Identifiers
| Name | sibutramine hydrochloride |
| Synonyms | tdfeind MERIDIA REDUCTIL BTS 54524 SIBUTRAMINE HCL Sibutramine·HCL Sibutramine Hcl SIBUTRAMINEHYDROCHLORIDE sibutramine hydrochloride SIBUTRAMINE HYDROCHLORIDE Intermediate of Sibutramine hydrochloride 1-[2-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine 1-(4-CHLOROPHENYL)-N,N-DIMETHYL-BETA-(2-METHYLPROPYL)CYCLOBUTANEMETHANAMINE HYDROCHLORIDE |
| CAS | 84485-00-7 |
| InChI | InChI=1/C17H26ClN/c1-12(2)11-17(19(3)4)16-10-9-15(16)13-5-7-14(18)8-6-13/h5-8,12,15-17H,9-11H2,1-4H3 |
SIBUTRAMINE HCL - Physico-chemical Properties
| Molecular Formula | C17H27Cl2N |
| Molar Mass | 316.31 |
| Density | 1.026g/cm3 |
| Melting Point | 190-200°C |
| Boling Point | 348.119°C at 760 mmHg |
| Flash Point | 164.337°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | room temp |
| Refractive Index | 1.527 |
SIBUTRAMINE HCL - Nature
Open Data Verified Data
colorless or white crystal, melting point 193~195,5.
Last Update：2024-01-02 23:10:35
SIBUTRAMINE HCL - Preparation Method
Open Data Verified Data
sibutramine was dissolved in methanol, and concentrated hydrochloric acid was added to complete the reaction. At least the amount of methanol was recovered under reduced pressure to crystallize out, water was added, stirred, and cooled in an ice bath. Filtration, washing, give sibutramine hydrochloride crude, with methanol water recrystallization, give white crystals of sibutramine hydrochloride.
Last Update：2022-01-01 09:24:16
SIBUTRAMINE HCL - Use
Open Data Verified Data
developed by Knoll, Inc., Germany, was first launched in the United States in April 1998. As a norepinephrine and 5-HT reuptake inhibitor, sibutramine acts primarily through its metabolites. It can increase physiological satiety, reduce appetite, induce heat production and increase energy consumption by inhibiting the reuptake of monoamine information transmission factors such as 5-HT and norepinephrine, decreased fat accumulation. Obesity Treatment for diet control, exercise failure to reduce and control weight.
Last Update：2022-01-01 09:24:16
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